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methotrexate gives women the opportunity to have a termination performed as early as a week prior to missing their period up to 9 weeks from the last menstrual period.

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prolonged cyclic combination with cyclophosphamide, methotrexate and fluorouracil has given good results when used as adjuvant treatment to radical mastectomy in primary breast cancer with positive axillary lymph nodes.

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methotrexate leads to diminished production of leukotriene b4 by neutrophils stimulated ex vivo.

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